| Product Name | MBP, MAPK Substrate, Biotinylated, Phosphorylated |
| Purity | HPLC>95% |
| Description | This is an N-terminal biotinylated peptide with phosphorylated Thr97. The sequence aprtpgrr contains a natural sequence derived from amino acids 95-98 of bovine myelin basic protein (PRTP). The rest of the sequence is not derived from the local sequence, but a synthetic structure. aprtpgrr is specific to MAP kinases: p44MAPK [extracellular signal-regulated kinase 1 (ERK1)] and p42MAPK (ERK2). It contains the consensus sequence Pro-X-(Ser/Thr)-Pro recognized by MAP kinase. aprtpgrr is the most effective substrate for the phosphorylation of ERK. It can be phosphorylated by the kinase on threonine 97 or by MAPK p38. |
| Storage | -20°C |
| References | Ref: Sommer, F. et al. Int. J. Impot. Res. 14, 217 (2002); Lents, NH. et al. Ann. N. Y. Acad. Sci. 973, 265 (2002); Kameshita, I. et al. J. Biochem. (Tokyo) 122, 168 (1997). |
| Molecular Weight | 1273.4 |
| Sequence (One-Letter Code) | Biotin-APR-pT-PGGRR |
| Sequence (Three-Letter Code) | Biotin - Ala - Pro - Arg - pThr - Pro - Gly - Gly - Arg - Arg - OH |
MBP, MAPK Substrate, Biotinylated, PhosphorylatedAdmin2021-01-13T11:19:32+00:00
