| Product Name | [Lys(Ac)12]-Histone H4 (1-20), H4K12(Ac) |
| Purity | HPLC>95% |
| Description | This peptide is histone 4 acetylation at lysine 12. Based on genome-wide localization studies, it was found that the peptide occupies the promoter region at the transcription start site, especially related to specific promoters, which may drive high-level mRNA transcripts stored in mature sperm. These observations led to the hypothesis that H4K12Ac may be one of the epigenetic markers of developmental genes. |
| Storage | -20°C |
| References | 1, Borra, MT. et al. Biochem. 43, 9877 (2004) 2, Paradowska AS. et al. Epigen, 7(9):1057-70 (2012). |
| Molecular Weight | 2034.4 |
| Sequence (One-Letter Code) | SGRGKGGKGLG-K(Ac)-GGAKRHRK |
| Sequence (Three-Letter Code) | H - Ser - Gly - Arg - Gly - Lys - Gly - Gly - Lys - Gly - Leu - Gly - Lys(Ac) - Gly - Gly - Ala - Lys - Arg - His - Arg - Lys - OH |
[Lys(Ac)12]-Histone H4 (1-20), H4K12(Ac)Admin2021-01-12T12:15:17+00:00
