Product Name | G209-2M, gp100 (209-217) |
Purity | HPLC>95% |
Description | This modified gp100 peptide amino acids 209 to 217 is a MHC-associated HLA-A2.1-restricted epitope derived from melanoma antigene. It can be processed, presented, and recognized by T cells. Alteration of the G209 peptide to G209-2M at the second amino acid changing threonine to a methionine was found to increase the affinity for MHC-associated HLA-A2.1 resulting in enhanced induction of T cells reactive to native gp100 |
Storage | -20°C |
References | Schaed, S. et al. Clin. Canc. Res. 8, 967 (2002); Paczesny, S. et al. JEM 199, 1503 (2004). |
Molecular Weight | 1035.2 |
Sequence (One-Letter Code) | IMDQVPFSV |
Sequence (Three-Letter Code) | H - Ile - Met - Asp - Gln - Val - Pro - Phe - Ser - Val - OH |
G209-2M, gp100 (209-217)Admin2021-01-06T05:53:04+00:00