| Product Name | Biotin-LC-Angiotensin II |
| Purity | HPLC>95% |
| Description | This octapeptide Angiotensin II, DRVYIHPF, is biotinylated on the N-terminus via an LC (long chain, also known as 6-Aminohexanoyl, 6-Aminocaproyl or Ahx) linker. It can be used in ELISA assay. Angiotensin II (Ang II) exerts a wide range of effects on the cardiovascular system. It is also implicated in the regulation of cell proliferation, fibrosis and apoptosis. Ang II is formed by cleavage of Ang I by the angiotensin-converting enzyme (ACE) or chymases. Human heart chymase, a chymotrypsin-like serine proteinase, hydrolyzes the Phe8-His9 bond to yield the octapeptide hormone angiotensin II and His-Leu. |
| Storage | -20°C |
| References | 1, Cobb, C. et al. Gen Comp Endocrinol 127, 8 (2002) 2, Lundequist, A. et al. J Biol Chem 279, 32339 (2004) 3, Kinoshita, A. et al. J Biol Chem 266, 19192 (1991) 4, Spyroulias, G. et al. Eur J Biochem 270, 2163 (2003). |
| Molecular Weight | 1385.7 |
| Sequence (One-Letter Code) | Biotin-LC-DRVYIHPF |
| Sequence (Three-Letter Code) | Biotin - LC - Asp - Arg - Val - Tyr - Ile - His - Pro - Phe - OH |
Biotin-LC-Angiotensin IIAdmin2021-01-04T10:33:28+00:00
