| Product Name | Bid BH3-r8 |
| Purity | HPLC>95% |
| Description | The Bid BH3 is a pro-apoptotic member of the 'BH3-only' subset of BCL-2 family proteins that constitute a critical control point in apoptosis. r8BIDBH3 is lethal to human leukemia cell lines that expresse Bcl-2. The Bcl-2 antagonists may have the potential to be efficacious in cancer therapy. Poly-D-arginine (d-isomer as denoted by rrrrrrrr) is fused to the Bid BH3 peptide to facilitate cellular uptake of the peptide. |
| Storage | -20°C |
| References | Letai, A. J.Clin. Invest. 115, 2648 (2005); Mendoza, F. et al. Arch. Immunol. Ther. Exp. 53, 47 (2002). |
| Molecular Weight | 3616.2 |
| Sequence (One-Letter Code) | rrrrrrrr-GEDIIRNIARHLAQVGDSMDR |
| Sequence (Three-Letter Code) | H - D - Arg - D - Arg - D - Arg - D - Arg - D - Arg - D - Arg - D - Arg - D - Arg - Gly - Glu - Asp - Ile - Ile - Arg - Asn - Ile - Ala - Arg - His - Leu - Ala - Gln - Val - Gly - Asp - Ser - Met - Asp - Arg |
Bid BH3-r8Admin2021-01-06T05:44:08+00:00
