| Product Name | Annexin A1 (1-25) (dephosphorylated) (human) |
| Purity | HPLC>95% |
| Description | Annexin A1 (AnxA1) N-terminal derivative peptide, also known as Ac2-26, mimics the anti-inflammatory effect of AnxA1. Ac2-26 can activate all three formyl peptide receptor family members FPR, FPR-like (FPRL) 1 and FPRL2 at similar concentrations. It represents the first endogenous ligand of FPRL2. In myocardial ischemia-reperfusion injury experiments, the peptide showed cardioprotective effects. Understanding the underlying mechanisms may help develop new therapies for acute cardioprotection. |
| Storage | -20°C |
| References | B.A.Babbin et al., J. Biol. Chem., 281, 19588 (2006)F.N.Gavins et al., FASEB J., 19, 100 (2005)R.H.Ritchie et al., Br. J. Pharmacol., 145, 495 (2005)S.Ernst et al., J. Immunol., 172, 7669 (2004)M.Perretti and R.J.Flower, Pharmacol. Res., 30, 53 (1994) |
| Molecular Weight | 3089.47 |
| Sequence (One-Letter Code) | Ac-AMVSEFLKQAWFIENEEQEYVQTVK |
| Sequence (Three-Letter Code) | Ac-Ala-Met-Val-Ser-Glu-Phe-Leu-Lys-Gln-Ala-Trp-Phe-Ile-Glu-Asn-Glu-Glu-Gln-Glu-Tyr-Val-Gln-Thr-Val-Lys-OH |
Annexin A1 (1-25) (dephosphorylated) (human)Admin2021-01-17T11:30:02+00:00
