| Product Name | α-Synuclein (45-54) (human) |
| Purity | HPLC>95% |
| Description | Aggregation of α-synuclein (α-syn) into toxic fibrils is a pathogenic hallmark of Parkinson’s disease (PD). Most early onset mutations are located between residues 46-53. The sequence of α-synuclein (45-54) was used by Cheruvara and coworkers as a template for a peptide library. The authors isolated a 10-residue peptide antagonist that potently inhibits α-synuclein aggregation and associated toxicity at 1:1 stoichiometry. |
| Storage | -20°C |
| References | H.Cheruvara et al., J. Biol. Chem., 290, 7426 (2015) |
| Molecular Weight | 996.12 |
| Sequence (One-Letter Code) | KEGVVHGVAT |
| Sequence (Three-Letter Code) | H-Lys-Glu-Gly-Val-Val-His-Gly-Val-Ala-Thr-OH |
α-Synuclein (45-54) (human)Admin2020-12-18T13:11:50+00:00
