| Product Name | (Pyr¹¹)-Amyloid β-Protein (11-40) |
| Purity | HPLC>95% |
| Description | pEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV, the N-terminally truncated isoform of the amyloid β-protein (Aβ) beginning with a pyroglutamate (Pyr) residue at position 11 was used in experiments studying the generality of fibrillogenesis-related helix formation. Comparing the fibrillogenesis kinetics of many of the most important clinically relevant amyloid β-protein alloforms it could be observed that among these peptides (Pyr¹¹)-amyloid β-protein (11-40) exhibited the greatest retardation of fibrillization rate. |
| Storage | -20°C |
| References | S.S.Mok et al., J. Neurosci. Res., 61, 449 (2000) W.He and C.J.Barrow, Biochemistry, 38, 10871 (1999) C.Russo et al., FEBS Lett., 409, 411 (1997) |
| Molecular Weight | 3133.67 |
| Sequence (One-Letter Code) | Pyr-VHHQKLVFFAEDVGSNKGAIIGLMVGGVV |
| Sequence (Three-Letter Code) | Pyr-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-OH |
(Pyr¹¹)-Amyloid β-Protein (11-40)Admin2020-12-18T11:52:17+00:00
