| Product Name | Ac-APP₇₇₀ (96-110) (cyclized) |
| Purity | HPLC>95% |
| Description | This cyclized peptide which is homologous to the heparin-binding domain of APP, binds strongly to heparin and inhibits binding of ¹²⁵I-labeled APP to heparin (IC₅₀= 10⁻⁷M). The peptide blocks the heparan sulfate proteoglycan-dependent stimulatory effect of APP on neurite outgrowth. |
| Storage | -20°C |
| References | D.H.Small et al., J. Neurosci., 14, 2117 (1994) |
| Molecular Weight | 1918.24 |
| Sequence (One-Letter Code) | Ac-NWCKRGRKQCKTHPH-NH₂ (Disulfide bond) |
| Sequence (Three-Letter Code) | Ac-Asn-Trp-Cys-Lys-Arg-Gly-Arg-Lys-Gln-Cys-Lys-Thr-His-Pro-His-NH₂ (Disulfide bond) |
Ac-APP₇₇₀ (96-110) (cyclized)Admin2020-12-18T12:26:52+00:00
