| Product Name | Macropin 2 |
| Purity | HPLC>95% |
| Description | Thisanti-microbial peptide (AMP) has been shown to cause lysis of several human cancer cell lines. Macropin-2 is most potent against CCRF-CEM T lymphoblastoid (human acute lymphoblastic leukemia) cells. At higher concentrations Macropin-2 also causes lysis of human umbilical vein endothelial cells (HUVEC), rat intestinal epithelial cells (IEC), human cervix carcinoma (HeLa) cells and human colon adenocarcinoma (SW480). |
| Storage | -20°C |
| References | Slaninová et al (2012) Toxicity study of antimicrobial peptides from wild bee venom and their analogs toward mammalian normal and cancer cells. Peptides 33(1) 18 PMID: 22100226 Tonk et al (2016) Insect antimicrobial peptides: potential tools for the prevention of skin cancer. Appl. Microbiol. Biotechnol. 100(17) 7397 PMID: 27418360 |
| Molecular Weight | 2007.53 |
| Sequence (One-Letter Code) | GTGLPMSERRKIMLMMR-acid |
| Sequence (Three-Letter Code) | H-Gly-Thr-Gly-Pro-Met-Ser-Arg-Arg-Lys-Ile-Met-Leu-Met-Met-Arg-OH |
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