| Product Name | Pannexin-1 (Panx1), Mimetic Blocking Peptide |
| Purity | HPLC>95% |
| Description | This is a pannexin-1 (Panx1) mimic blocking peptide. Pannexin-1 is a recently identified membrane protein. When overexpressed in two adjacent oocytes or mammalian epithelial cell lines, it can form gap junction-like connections to allow the dye to pass between cells. The blockade of pannexin-1 in macrophages that endogenously express the ATP-gated P2X7 receptor (P2X7R) prevents the initial dye uptake, but does not block the ion current, and also blocks the processing and release of interleukin-1 . (IL-1?) In response to P2X7R activation. |
| Storage | -20°C |
| References | Pelegrin, P. et al. EMBO. J. 25, 5071 (2006); Pelegrin, P. et al.t J. Biol. Chem. 282, 2386 (2007). |
| Molecular Weight | 1242.4 |
| Sequence (One-Letter Code) | WRQAAFVDSY |
| Sequence (Three-Letter Code) | H - Trp - Arg - Gln - Ala - Ala - Phe - Val - Asp - Ser - Tyr - OH |
Pannexin-1 (Panx1), Mimetic Blocking PeptideAdmin2021-01-16T11:46:26+00:00
