| Product Name | Cathepsin D and E FRET Substrate |
| Purity | HPLC>95% |
| Description | Cathepsins D and E obtained from the hepatopancreas (liver) of Japanese common squid (Todarodes pacificus) instead of B, H or L internal quenching fluorescent substrates (Ab / Em = 328/393 nm). Cleavage occurs at the Phe-Phe amide bond, resulting in increased fluorescence, and is used to screen cathepsin D and E inhibitors, and to determine the activity of cathepsin D and E in tissue cell extracts. |
| Storage | -20°C |
| References | Yasuda, Y. et al. J. Biochem. 125, 1137 (1999). |
| Molecular Weight | 1756.1 |
| Sequence (One-Letter Code) | Mca-GKPILFFRLK(Dnp)-r-NH2 |
| Sequence (Three-Letter Code) | 7 - Methoxycoumarin - 4 - Acetyl - Gly - Lys - Pro - Ile - Leu - Phe - Phe - Arg - Leu - Lys(Dnp) - D - Arg - NH2 |
Cathepsin D and E FRET SubstrateAdmin2021-01-16T10:14:17+00:00
