| Product Name | Orexin B, human |
| Purity | HPLC>95% |
| Description | Orexin is synthesized by the posterolateral neurons of hypothalamus. They bind to orexin-1 (OXR1) and orexin 2 (oxr2) receptors. Orexin A can bind to OXR1 and oxr2, while orexin B can only bind to oxr2. Both orexins are involved in the regulation of wakefulness and sleep, energy homeostasis and autonomic central control. |
| Storage | -20°C |
| References | 1. Martynska L., et.al., Neuroendocr Lett 4(26), 289-292 (2005). 2. Ebrahim I.O., et.al., J of Royl Soc of Med95, 227-230 (2002). 3. Ramanjaneya M., et.al., Endocrinology151 (7), 3169-3180 (2010). |
| Molecular Weight | 2898.9 |
| Sequence (One-Letter Code) | RSGPPGLQGRLQRLLQASGNHAAGILTM-NH2 |
| Sequence (Three-Letter Code) | Arg - Ser - Gly - Pro - Pro - Gly - Leu - Gln - Gly - Arg - Leu - Gln - Arg - Leu - Leu - Gln - Ala - Ser - Gly - Asn - His - Ala - Ala - Gly - Ile - Leu - Thr - Met - NH2 |
Orexin B, humanAdmin2021-01-15T10:21:43+00:00
