Product Name | [Lys(Ac)8]-Histone H4 (1-20), H4K8(Ac) |
Purity | HPLC>95% |
Description | This is a histone 4 peptide acetylated with lysine 8. In some studies, this histone modification is thought to predict the prognosis of resected non-small cell lung cancer. This peptide has also been shown to play a role in somatic hypermutation (SHM), because its modification may mediate the recruitment of error-prone DNA polymerases during the DNA repair phase of SHM. |
Storage | -20°C |
References | 1, Borra, MT. et al. Biochem. 43, 9877 (2004) 2, Barlesi F. et al. J Clin Oncol, 25(28):4358-4364 (2007) 3, Guideng Li. Et al. Trends Immunol, 34(9):460-470 (2013). |
Molecular Weight | 2034.4 |
Sequence (One-Letter Code) | SGRGKGG-K(Ac)-GLGKGGAKRHRK |
Sequence (Three-Letter Code) | H - Ser - Gly - Arg - Gly - Lys - Gly - Gly - Lys(Ac) - Gly - Leu - Gly - Lys - Gly - Gly - Ala - Lys - Arg - His - Arg - Lys - OH |
[Lys(Ac)8]-Histone H4 (1-20), H4K8(Ac)Admin2021-01-12T12:04:16+00:00