Product Name | [Cit 2/8/17]-Histone H3 (1-21)-GGK(Biotin), amide |
Purity | HPLC>95% |
Description | This is histone H3 (1-21), in which Arg2, Arg8 and Arg17 are deaminated to citrulline (Cit). Its C-terminus is biotinylated by the GGK linker and blocked by an amide group. Peptidyl arginine deaminase 4 (PADI4) prevents the methylation of these sites and blocks transcriptional activation. When the peptide purity is greater than 95%, the peptide is dissolved in distilled water at a concentration of 1 mg/ml, and lyophilized again into a powder form. |
Storage | -20°C |
References | Cuthbert, G. et al. Cell 118, 545 (2004). |
Molecular Weight | 2725.2 |
Sequence (One-Letter Code) | A-Cit-TKQTA-Cit-KSTGGKAP-Cit-KQLAGG-K(Biotin)-NH2 |
Sequence (Three-Letter Code) | H - Ala - Cit - Thr - Lys - Gln - Thr - Ala - Cit - Lys - Ser - Thr - Gly - Gly - Lys - Ala - Pro - Cit - Lys - Gln - Leu - Ala - Gly - Gly - Lys(Biotin) - NH2 |
[Cit 2/8/17]-Histone H3 (1-21)-GGK(Biotin), amideAdmin2021-01-08T06:54:03+00:00