Product Name | Biotin-Glucagon (1-29), bovine, human, porcine |
Purity | HPLC>95% |
Description | This is n-terminal biotin-labeled glucagon (1-29). Glucagon is a peptide hormone that is secreted by the Langerhans alpha cells of the pancreatic islets in response to low circulating blood sugar levels to restore normal glucose levels. It acts on liver enzymes that regulate glucose production and glycogen synthesis. Excessive levels of glucagon in the circulation are related to metabolic disorders in type 2 diabetes, because this condition can lead to high blood sugar. |
Storage | -20°C |
References | O'Harte. FP. et. al. Mol Cell Endocrinol 381, 26 (2013), doi: 10.1016/j.mce.2013.07.014 Drucker DJ. Endocrinology: Adult and Pediatric (7th Ed.) 1, 586 (2016), doi:10.1016/B978-0-323-18907-1.00034-2 |
Molecular Weight | 3709.1 |
Sequence (One-Letter Code) | Biotin-HSQGTFTSDYSKYLDSRRAQDFVQWLMNT |
Sequence (Three-Letter Code) | Biotin - His - Ser - Gln - Gly - Thr - Phe - Thr - Ser - Asp - Tyr - Ser - Lys - Tyr - Leu - Asp - Ser - Arg - Arg - Ala - Gln - Asp - Phe - Val - Gln - Trp - Leu - Met - Asn - Thr - OH |
Biotin-Glucagon (1-29), bovine, human, porcineAdmin2021-01-07T06:59:57+00:00