| Product Name | HIF-1 {alpha} (556-574) |
| Purity | HPLC>95% |
| Description | This is a hypoxia-inducible factor-1 (HIF-1 a) 19-mer fragment. HIF-1 functions as master regulator of response to oxygen homeostasis. Hypoxia-induced gene expression is initiated when HIF-1 subunit is stabilized in response to a lack of oxygen. This part of HIF-1 binds to the von Hippel-Lindau factor (VHL) an E3 ubiquitin ligase, and the proline 564 is absolutely critical to the binding process |
| Storage | -20°C |
| References | Hirsilä, M. et al. J Biol. Chem 278, 30772 (2003); Robinson, B. Pediatric Research 50, 673 (2001). |
| Molecular Weight | 2254.6 |
| Sequence (One-Letter Code) | DLDLEMLAPYIPMDDDFQL |
| Sequence (Three-Letter Code) | H - Asp - Leu - Asp - Leu - Glu - Met - Leu - Ala - Pro - Tyr - Ile - Pro - Met - Asp - Asp - Asp - Phe - Gln - Leu - OH |
HIF-1 {alpha} (556-574)Admin2021-01-06T05:58:17+00:00
