Product Name | Bid BH3 Peptide |
Purity | HPLC>95% |
Description | BID is a pro-apoptotic member of the 'BH3-only' (BOPS) subset of the BCL-2 family of proteins that constitute a critical control point in apoptosis. Bid is the first of the BOPs reported to bind and activate Bcl-2, Bax, and Bak. Bid serves as a death-inducing ligand that moves from the cytosol to the mitochondrial membrane to inactivate Bcl-2 or to activate Bax. |
Storage | -20°C |
References | Oh, K. J. et al J. Biol. Chem. 280, 753 (2005); Oh, K. J. et al. J. Biol. Chem. 281, 36999 (2006); Manero, F. et al. Cancer Res. 66, 2757 (2006); Zhai, D. et al. J. Biol. Chem. 280, 15815 (2005); Walensky, L. et al. Mol. Cell. 24, 199 (2006); Onuki, R. et al. Proc. Natl. Acad. Sci. U S A 99, 14716 (2002); Wang, K. Gen. Develop. 10, 2859 (1996). |
Molecular Weight | 2309.6 |
Sequence (One-Letter Code) | EDIIRNIARHLAQVGDSMDR |
Sequence (Three-Letter Code) | H - Glu - Asp - Ile - Ile - Arg - Asn - Ile - Ala - Arg - His - Leu - Ala - Gln - Val - Gly - Asp - Ser - Met - Asp - Arg - OH |
Bid BH3 PeptideAdmin2021-01-06T05:37:14+00:00