| Product Name | Bax BH3 peptide (55-74), wild type |
| Purity | HPLC>95% |
| Description | This is a 20–amino acid Bax BH3 peptide (Bax 1) capable of inducing apoptosis in a variety of cell line models. In addition to disrupting Bax/Bcl-2 and Bax/Bcl-XL, it can promote cytochrome c release from isolated mitochondria. Bax BH3 belongs to the Bcl-2 protein family which consists of both pro-apoptotic and anti-apoptotic members. Bax BH3 acts to regulate apoptosis via governance of the 'intrinsic' pathway of cell death. |
| Storage | -20°C |
| References | Shangary, S. et al. Mol. Canc. Ther. 3, 1343 (2004); Shangary, S. et al. Biochem. 41, 9485 (2002). |
| Molecular Weight | 2267.6 |
| Sequence (One-Letter Code) | STKKLSECLKRIGDELDSNM |
| Sequence (Three-Letter Code) | H - Ser - Thr - Lys - Lys - Leu - Ser - Glu - Cys - Leu - Lys - Arg - Ile - Gly - Asp - Glu - Leu - Asp - Ser - Asn - Met - OH |
Bax BH3 peptide (55-74), wild typeAdmin2021-01-05T06:33:22+00:00
