| Product Name | Pap12-6 |
| Purity | HPLC>95% |
| Description | Broad-spectrum antibacterial, active against multidrug-resistant Gram-negative bacteria. Acts though permeabilizing the bacterial membrane and also shows anti-inflammatory activity via a TLR4-mediated NF-κB signaling pathway. Significantly improves survival in a mouse sepsis model. |
| Storage | -20°C |
| References | Kim et al (2019) Development of a novel short 12-meric papiliocin-derived peptide that is effective against Gram-negative sepsis. Sci. Rep. 9 3817 PMID: 30846839 |
| Molecular Weight | 1644.1 |
| Sequence (One-Letter Code) | RWKIFKKVVKKW-amide |
| Sequence (Three-Letter Code) | H-Arg-Trp-Lys-Ile-Phe-Lys-Lys-Val-Val-Lys-Lys-Trp-NH2 |
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