| Product Name | Melittin |
| Purity | HPLC>95% |
| Description | Melittin is a 26-residue peptide originally isolated from venom of the European honeybee. Melittin is a cationic, hemolytic peptide from honey bee venom. Melittin lowers the surface tension at the plasma membrane and causes cell lysis. Melittin exhibits potent anti-inflammatory and antimicrobial activity. Melittin has been extensively used as a model peptide for observing membrane lipid-protein interactions |
| Storage | -20°C |
| References | Raghuraman H Biosci Rep. 2007 Oct;27(4-5):189-223. 2. Fukushima et al (1998) Melittin, a metabostatic peptide inhibiting Gs activity. Peptides 5 811. PMID: 9663445. 3. Raynor et al (1991) J.Biol.Chem. 266 2753. PMID: 1847132. 4. Mousli et al (1990) TiPS 11 358. PMID: 2122563. 1. 5. Ming-Tao Lee PNAS 2013 110 (35) 14243-14248 2. 6. Lee et al. PNAS (2013) 110(35): 14243-14248 |
| Molecular Weight | 2075.67 |
| Sequence (One-Letter Code) | GIGAVLKVLTTGLPALISWIKRKRQQ-amide |
| Sequence (Three-Letter Code) | H-Gly-Ile-Gly-Ala-Val-Leu-Lys-Val-Leu-Thr-Thr-Gly-Leu-Pro-Ala-Leu-Ile-Ser-Trp-Ile-Lys-Arg-Lys-Arg-Gln-Gln-NH2 |
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