| Product Name | Acetyl-Alpha-synuclein (1-13) Met5(O) Heavy |
| Purity | HPLC>95% |
| Description | Acetylated α-synuclein (1-13) is derived from the alpha-synuclein intrinsically disordered protein which is found in the neurons and presynaptic terminals. The N-terminal acetylation of alpha-synuclein can alter the rates of alpha-synuclein aggregation. The methionine at position 5 is oxidised and the leucine residue at position 8 is isotopically labelled with carbon-13(6) and nitrogen-15(1). |
| Storage | -20°C |
| References | Binolfi et al (2016) Intracellular repair of oxidation-damaged α-synuclein fails to target C-terminal modification sites. Nat. Commun. 7 10251 https://doi.org/10.1038/ncomms10251 |
| Molecular Weight | 1547.8 |
| Sequence (One-Letter Code) | Ac-MDVF-[Met(O)]-KG-[U-13C6,15N-Leu]-SKAKE-acid, where Met(O) is oxidised Methionine |
| Sequence (Three-Letter Code) | Met-Asp-Val-Phe-[Met(O)]-Lys-Gly-[U-13C6,15N-Leu]-Ser-Lys-Ala-Lys-Glu-OH |
Acetyl-Alpha-synuclein (1-13) Met5(O) HeavyAdmin2020-12-18T12:27:52+00:00
